Utilização de pastas contendo fosfopeptídeo de caseína-fosfato de cálcio amorfo com e sem fluoreto na prevenção da erosão dentária: uma revisão da literatura
DOI:
https://doi.org/10.21270/archi.v6i11.2254Resumo
Introdução: A erosão dentária caracteriza-se como uma perda progressiva de estrutura dentária em que ocorre dissolução localizada de minerais da superfície do dente, ocasionada devido a exposição a ácidos de origem não bacteriana. Esse agravo bucal tem ganhado destaque pelo aumento de sua prevalência, que tem ocorrido, principalmente, devido a mudança dos hábitos alimentares e no estilo de vida da sociedade moderna. Objetivo: Apresentar uma síntese da ação das pastas de CPP-ACP no controle da erosão dentária. Material e Método: Foi realizada uma revisão da literatura nas bases de dados eletrônicas: Pubmed, Scopus e Bireme, utilizando os termos Erosão Dentária, Tooth Erosion, Esmalte Dentário, Dental Enamel, Caseínas, Caseins, Fluoreto de Sódio, Sodium Fluoride e os operadores boleanos “AND” e “OR” para realização das buscas, não havendo restrição quanto ao ano ou idioma de publicação. Resultados: Diferentes condutas terapêuticas têm sido avaliadas como potenciais alternativas para o controle da erosão dentária, dentre os quais está o uso da caseína fosfopeptídeo - fosfato de cálcio amorfo (CPP-ACP). As pastas de CPP-ACP parecem ser o tipo de veículo com maior potencial preventivo, além disso, a literatura sugere também, que as abordagens adotadas previamente às exposições ácidas tendem a ser mais bem-sucedidas. Apesar disso, ainda não há um consenso sobre a eficácia desse recurso terapêutico, devido, principalmente a carência de estudos realizados sob protocolos in situ. Conclusão: A ação preventiva das pastas de CPP-ACP, suplementadas ou não pelo fluoreto, permanece incipiente na literatura.Descritores: Erosão Dentária; Esmalte Dentário; Caseínas; Fluoreto de Sódio.
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Referências
Amaechi BT, Higham SM. Dental erosion: possible approaches to prevention and control. J Dent. 2005; 33(3):243-52.
Magalhães AC, Wiegand A, Rios D, Buzalaf MAR, Lussi A. Fluoride in dental erosion. Monogr Oral Sci. 2011; 22:158-70.
Wang CP, Huang SB, Liu Y, Li JY, Yu HY. The CPP-ACP relieved enamel erosion from a carbonated soft beverage: an in vitro AFM and XRD study. Arch Oral Biol. 2014; 59(3):277-82.
Diniz MB, Lussi A. Dental Erosion in Pediatric Dentistry: What is the Clinical Relevance? Pesqui Bras Odontoped Clin Integr. 2017; 17(1):e3592.
Zawaideh FI, Owais AI, Mushtaha S. Effect of CPP-ACP or a Potassium Nitrate Sodium Fluoride Dentifrice on Enamel Erosion Prevention. J Clin Pediatr Dent. 2017; 41(2):135-40.
Buzalaf MA, Hannas AR, Kato MT. Saliva and dental erosion. J Appl Oral Sci. 2012; 20(5):493-502.
Shellis RP, Addy M. The interactions between attrition, abrasion and erosion in tooth wear. Monogr Oral Sci. 2014; 25:32-45.
Salas MM, Nascimento GG, Vargas-Ferreira F, Tarquinio SB, Huysmans MC, Demarco FF. Diet influenced tooth erosion prevalence in children and adolescents: Results of a meta-analysis and meta-regression. J Dent. 2015; 43(8):865-75.
Mafla AC, Cerón-Bastidas XA, Munoz-Ceballos ME, Vallejo-Bravo DC, Fajardo-Santacruz MC. Prevalence and extrinsic risk factors for dental erosion in adolescentes. J Clin Pedriatr Dent. 2017; 41(2):102-11.
Wiegand A, Wegehaupt F, Werner C, Attin T. Susceptibility of acid-softened enamel to mechanical wear - ultrasonication versus toothbrushing abrasion. Caries Res. 2007; 41(1):56-60.
Kanzow P, Wegehaupt FJ, Attin T, Wiegand A. Etiology and pathogenesis of dental erosion. Quintessence Int. 2016; 47(4):275-8.
Huysmans MC, Chew HP, Ellwood RP. Clinical studies of dental erosion and erosive wear. Caries Res. 2011; 45(Suppl l):60-8.
Reynolds EC. Casein phosphopeptide-amorphous calcium phosphate: the scientific evidence. Adv Dent Res. 2009; 21(1):25-9.
Cassiano LP, Charone S, Souza JG, Leizico LC, Pessan JP, Magalhães AC et al. Protective Effect of Whole and Fat-Free Fluoridated Milk, Applied before or after Acid Challenge, against Dental Erosion. Caries Res. 2016; 50(2):111-6.
White AJ, Jones SB, Barbour ME, Churchley DR, Gracia LH, Rees GD. Inhibition of erosive dissolution by sodium fluoride: evidence for a dose-response. J Dent. 2012; 40(8):654-60.
Huysmans MC, Young A, Ganss C. The role of fluoride in erosion therapy. Monogr Oral Sci. 2014; 25:230-43.
Tantbirojn D, Huang A, Ericson MD, Poolthong S. Change in surface hardness of enamel by a cola drink and a cpp-acp paste. J Dent. 2008; 36(1):74-9.
Peutzfeldt A, Jaeggi T, Lussi, A. Restorative therapy of erosive lesions. Monogr Oral Sci. 2014; 25:253-61.
Turssi CP, Maeda FA, Messias DC, Neto FC, Serra MC, Galafassi D. Effect of potential remineralizing agents on acid softened enamel. Am J Dent. 2011; 24(3):165-8.
Magalhães AC, Wiegand A, Rios D, Honório HM, Buzalaf MA. Insights into preventive measures for dental erosion. J Appl Oral Sci. 2009; 17(2):75-86.
Lussi A. Introduction stabilized stannous fluoride and dental erosion. Int Dent J. 2014; 64(Suppl 1):2-3.
Rios D, Honório HM, Magalhães AC, Delbem AC, Machado MA, Silva SM et al. Effect of salivary stimulation on erosion of human and bovine enamel subjected or not to subsequent abrasion: an in situ/ex vivo study. Caries Res. 2006; 40(3):218-23.
Ramalingam L, Messer LB, Reynolds EC. Adding Casein Phosphopeptide-amorphous Calcium Phosphate to Sports Drinks to Eliminate In Vitro Erosion. Pediatr Dent. 2005; 27(1):61-7.
Ferrazzano GF, Coda M, Cantile T, Sangianantoni G, Ingenito A. SEM investigation on casein phosphopeptides capability in contrasting cola drinks enamel erosion: an in vitro preliminary study. Eur J Paediatr Dent. 2012; 13(4):285-8.
Wang X, Megert B, Hellwig E, Neuhaus KW, Lussi A. Preventing erosion with novel agents. J. Dent. 2011; 39(2):163-70.
Baumann T, Kozik J, Lussi A, Carvalho TS. Erosion protection conferred by whole human saliva, dialysed saliva, and artificial saliva. Sci Rep. 2016; 6:34760.
Kensche A, Pötschke S, Hannig C, Richter G, Hoth-Hannig W, Hannig M. Influence of Calcium Phosphate and Apatite Containing Products on Enamel Erosion. ScientificWorldJournal. 2016; 2016:7959273.
João-Souza SH, Bezerra SJ, Borges AB, Aranha AC, Scaramucci T. Effect of sodium fluoride and stannous chloride associated with Nd: YAG laser irradiation on the progression of enamel erosion. Lasers Med Sci. 2015; 30(9):2227-32.
Buzalaf MA, Magalhães AC, Wiegand A. Alternatives to fluoride I the prevention and treatment of dental erosion. Monogr Oral Sci. 2014; 25(1):244-52.
Somani R, Jaidka S, Singh DJ, Arora V. Remineralizing potential of various agents on dental erosion. J Oral Biol Craniofac Res. 2014; 4(2):104-8.
Algarni AA, Mussi MC, Moffa EB, Lippert F, Zero DT, Siqueira WL et al. The impact of stannous, fluoride ions and its combination on enamel pellicle proteome and dental erosion prevetion. Plos One. 2015; 10(6):e0128196.
de Alencar CR, Magalhães AC, de Andrade Moreira Machado MA, de Oliveira TM, Honório HM, Rios D. In situ effect of a commercial CPP-ACP chewing gum on the human enamel initial erosion. J Dent. 2014; 42(11):1502-7.
White AJ, Gracia LH, Barbour ME. Inhibition of dental erosion by casein and casein-derived proteins. Caries Res. 2010; 45(1):13-20.
Zheng L, Zheng J, Zhang YF, Quian LM, Zhou ZR. Effect of CPP-ACP on the remineralization of acid-eroded human tooth enamel: nanomechanical properties and microtribological behaviour study. J Phys D Appl Phys. 2013; 46(40): 404006.
Poggio C, Lombardini M, Vigorelli P, Ceci M. Analysis of dentin/enamel remineralization by a CPP-ACP paste: AFM and SEM study. Scanning. 2013; 35(6):366-74.
Srinivasan N, Kavitha M, Loganathan SC. Comparison of the remineralization potential of CPP-ACP and CPP-ACP with 900 ppm fluoride on eroded human enamel: an in situ study. Arch Oral Biol. 2010; 55(7):541-4.
Prestes L, Souza BM, Comar LP, Salomão PA, Rios D, Magalhães AC. In situ effect of chewing gum containing cpp-acp on the mineral precipitation of eroded bovine enamel- a surface hardness analysis. J Dent. 2013; 21(8):747-51.
Manton DJ, Cai F, Yuan Y, Walker GD, Cochrane NJ, Reynolds C, et al. Effect of casein phosphopeptide-amorphous calcium phosphate added to acidic beverages on enamel erosion in vitro. Aust Dent J. 2010; 55(3):275-9.
de Oliveira AF, de Oliveira Diniz LV, Forte FD, Sampaio FC, Ccahuana-Vásquez RA, Tochukwu Amaechi B. In situ effect of a CPP-ACP chewing gum on enamel erosion associated or not with abrasion. Clin Oral Investig. 2017; 21(1):339-46.
Ceci M, Mirando M, Beltrami R, Chiesa M, Poggio C. Protective effect of casein phosphopeptide-amorphous calcium phosphate on enamel erosion: atomic force microscopy studies. Scanning. 2015; 37(5):327-34.
Fita K, Kaczmarek U. The impact of selected fluoridated toothpastes on dental erosion in profilometric measurement. Adv Clin Exp Med. 2016; 25(2):327-33.
Oliveira DSB, Santin GC, Honório HM, Rios D, Gatón PH, Silva LAB et al. Single application of casein phosphopeptide-amorphous calcium phosphate paste-based paste prevents in vitro erosive wear. Eur J Gen Dent. 2016; 5(2):69-73.
Wegehaupt FJ, Tauböck TT, Stillhard A, Schmidlin PR, Attin T. Influence of extra and intra-oral application of CPP-ACP and fluoride on rehardening of eroded enamel. Acta Odontol Scand. 2012; 70(3):177-83.
Amaral CM, Miranda ME, Correa DS, Silva EM. Sodium fluoride and casein phosphopeptide-amorphous calcium phosphate cream plus sodium fluoride efficacy in preventing enamel erosion in a simulated oral environment study model. Indian J Dent Res. 2014; 25(4):464-9.
Wiegand A, Attin A. Randomised in situ trial on the effect of milk and cpp-acp on dental erosion. J Dent. 2014; 42(9):1210-5.
Jordão MC, Alencar CR, Mesquita IM, Buzalaf MA, Magalhães AC, Machado MA et al. In situ Effect of Chewing Gum with and without CPP-ACP on Enamel Surface Hardness Subsequent to ex vivo Acid Challenge. Caries Res. 2016; 50(3):325-30.
Rees J, Loyn T, Chadwick B. Pronamel and tooth mousse: an initial assessment of erosion prevention in vitro. J Dent. 2007; 35(4):355-7.
Carvalho FG, Brasil VL, Silva Filho TJ, Carlo HL, Santos RL, Lima BA. Protective effect of calcium nanophosphate and cpp-acp agents on enamel erosion. Braz Oral Res. 2013; 27(6):463-70.
Moezizadeh M, Alimi A. The effect of casein phosphopeptide-amorphous calcium phosphate paste and sodium fluoride mouthwash on the prevention of dentin erosion: an in vitro study. J Conserv Dent. 2014; 17(3):244-9.
Poggio C, Gulino C, Mirando M, Colombo M, Pietrocola G. Preventive effects of diferente protective agents on dentin erosion: An in vitro investigation. J Clin Exp Dent. 2017; 9(1):e7-12.
Alencar CRB, Oliveira GC, Magalhães AC, Buzalaf MAR, Machado MAAM, Honório HM, et al. In situ effect of CPP-ACP chewing gum upon erosive enamel loss. J Appl Oral Sci. 2017; 25(3):258-64.
Batista GR, Rocha Gomes Torres C, Sener B, Attin T, Wiegand A. Artificial Saliva Formulations versus Human Saliva Pretreatment in Dental Erosion Experiments. Caries Res. 2016; 50(1):78-86.
Alencar CR, Mendonça FL, Guerrini LB, Jordão MC, Oliveira GC, Honório HM et al. Effect of different salivary exposure times on the rehardening of acid-softened enamel. Braz Oral Res. 2016; 30(1):e104.
Bellamy PG, Harris R, Date RF, Mussett AJ, Manley A, Barker ML et al. In situ clinical evaluation of a stabilised, stannous fluoride dentifrice. Int Dent J. 2014; 64(Suppl 1):43-50.
