Manifestações orais de arboviroses com ênfase em dengue, zika e chikungunya: revisão de literatura

  • Amanda Alves de Oliveira
  • Maria Gabriella de Abreu Lacerda
  • Ariana Alves de Oliveira Barros
  • Jaqueline Oliveira Barreto
  • José Henrique de Araújo Cruz
  • Julliana Cariry Palhano Freire
  • Eduardo Dias Ribeiro
Palavras-chave: Infecções por Arbovirus, Dengue, Zika Virus, Vírus Chikungunya, Manifestações Bucais

Resumo

Introdução: A dengue, zika e chikungunya são doenças virais que podem ser classificadas como arboviroses. Suas complicações clínicas são de larga escala e podem acometer a cavidade oral. Objetivos: Realizar uma revisão na literatura científica sobre as manifestações clínicas na cavidade oral provocadas pelas arboviroses transmitidas pelo mosquito Aedes Egipty. Metodologia: foram analisados 69 artigos científicos obtidos nas bases de dados PubMed e Scielo correspondentes ao período de 2000 a 2018, tomando por base os seguintes descritores: “dengue”, “zika” e “chikungunya” em associação com o termo “oral manifestation(s)”. Resultados: Nas infecções por dengue clássica os relatos mais frequentes foram manifestações mucocutâneas, vermelhidão e edema nas mucosas, enquanto na dengue hemorrágica o sangramento gengival é tido como mais frequente seguido de focos hemorrágicos pelas demais regiões da mucosa bucal; já a zika mostrou-se presente na saliva, úlceras aftosas, paralisia facial e complicações orais relacionadas à microcefalia; nos casos de infecção pelo vírus chikingunya foram relatados dor, queimação e sangramento na gengiva, incapacidade de deglutir e mastigar, halitose e dor na abertura da boca.  Conclusão: Há manifestações orais durante a infecção por Dengue, Zika e Chikungunya demostrando assim, a importância e a necessidade da realização de maiores pesquisas neste campo para instituição de protocolo clínico.

Downloads

Não há dados estatísticos.

Referências

Freitas ARR, Angerami RN, von Zuben APB, Donalisio MR. Introduction and transmission of Zika virus in Brazil: new challenges for the Americas. Rev Inst Med Trop Sao Paulo. 2016;58:24.

Joshi V, Mouyra D, Sharma Rc. Persistence of dengue-3 virus through transovarial transmission passage in successive generations of Aedes aegypti mosquitoes. Am J Trop Med Hyg. 2002;67(2):158-61.

Srikiatkhachorn A, Krautrachue A, Ratanaprakarn W et al. Natural History of Plasma Leakage in Dengue Hemorrhagic Fever. The Pediatric Infectious Disease Journal. 2007;26(4):283-90.

Leão JC, Marques C, Duarte Um, de Almeida OP, Porter S, Gueiros LA. Chikungunya fever: General and oral healthcare implications. Oral Disease. 2018;24(1-2):233-37.

Diawo D, Amadou A. Sall, Cheikh T. Diagne, Oumar F, Ousmane F, Yamar Ba, et al. Zika virus emergence in mosquitoes in southeastern Senegal, 2011.PlosOne. 2014;9(10):109442.

Delatte H , Paupy C, Dehecq JS, Thiria J, Failloux AB, Fontenille D. [Aedes albopictus, vetor de vírus chikungunya e dengue na ilha da reunião: biologia e controle]. Parasite. 2008;15(1):3-13.

Kumar R, Sharma MK, Jain SK, Yadav SK, SinghalAK. Manifestações cutâneas da febre Chikungunya : observações de um surto em um hospital de cuidados terciários no sudeste de Rajasthan , na Índia. Indian Dermatol Online J. 2017 8(5):336-42.

Fernandes CI, Perez LE, Perez DE. Uncommon oral manifestations of dengue viral infection. Braz J Otorhinolaryngol. 2020;86:S3–S5.

Hasan S, Jamdar SF, Alalowi M, Al Ageel Al Beaiji SM. Dengue virus: A global human threat: Review of literature. J Int Soc Prev Community Dent. 2016;6(1):1-6.

Joob B, Wiwanitkit V. Oral manifestations of dengue viral infection. Braz J Otorhinolaryngol. 2017;83(5):605.

Pedrosa M, Pierote JA, Lopes LD, Pompeu JG. Manifestações orais relacionadas à dengue. Rev Assoc Paul Cir Dent. 2017;71(1):21-4.

Chadwick D, Arch B, Wilder-Smith A, Paton N. Distinguishing dengue fever from other infections on the basis of simple clinical and laboratory features: Application of logistic regression analysis. J Clin Virol. 2006;35(2):47-53.

Ávila MER, Rey YB, Valdés TA. Manifestaciones bucales del dengue. Acta Méd Centro. 2013;7(1):80-3.

Pontes FS, Frances LT, Carvalho M V, Fonseca FP, Neto NC, do Nascimento LS, Pontes HA. Severe oral manifestation of dengue viral infection: a rare clinical description. Quintessence Int. 2014;45(2):151-56.

Al-Namnam NM ,Nambiar P, Shanmuhasuntharam P, Harris M. A case of dengue-related osteonecrosis of the maxillary dentoalveolar bone. Aust Dent J. 2017;62(2): 228-32.

Joob B, Wiwanitkit V. Dengue and acute gingival bleeding. J Indian Soc Periodontol. 2014;18(1):4.

Mitra R, Baskaran P, Sathyakumar M. Oral presentation in hemorrhagic dengue: a rare entity. J Nat Sci Biol Med. 2013;4(1):264-67.

Amit Byatnal, Neha Mahajan, Shrinivas Koppal, Um Ravikiran, Thriveni R, Parvathi Devi MK. Unusual yet isolated oral manifestations of persistent thrombocytopenia: a rare case report. Braz J Oral Sci. 2013;12(3):233-36.

Mattos NF, Santos NA, Wingert GC, Pies S, Lara GM, Carvalho TS. Dengue: Uma visão imunológica. Newslab. 2015; 5(8):3-4.

Denis CK, Cavalcanti KM, Meirelles RC, Martinelli B, Valença DC. Otolaryngological manifestations of patients with dengue. Bras Otorrinolaringol.2019;69(5):644-47.

Jaganathan S, Raman R. Hypoglossal nerve palsy: A rare consequence of dengue fever. Neurol Índia.2014;62(5):567-68.

Musso D, Teissier A, Rouault E, Teururai S, de Pina JJ, Nhan TX. Detection of chikungunya virus in saliva and urine. Virol J. 2016;13:102.

Nicastri E, Castilletti C, Liuzzi G, Iannetta M, Capobianchi MR, Ippolito G. Persistent detection of Zika virus RNA in semen for six months after symptom onset in a traveller returning from Haiti to Italy, February 2016. Euro Surveill. 2016;21(32):303-14.

Fantinato F, Fontana S T, Lima Araújo L, Ribeiro IG, Andrade MR, Dantas ALM, et al.Descrição dos primeiros casos de febre pelo vírus Zika investigados em municípios da região Nordeste do Brasil, 2015. Epidemiol Serv Saúde. 2016;25(4): 683-90.

Bonaldo MC, Ribeiro IP, Lima NS, Santos AAC , Menezes LSR, Cruz SOD et al. Isolation of Infective Zika Virus from Urine and Saliva of Patients in Brazil. Plos Negl Trop Dis. 2016;10(6):4816.

Leão JC, Gueiros LA, Lodi G, Robinson NA, Scully C. Zika virus: oral healthcare implications. Oral Dis. 2017;23(1):12-7.

Smith DW, Mackenzie J. Zika virus and Guillain-Barré syndrome: another viral cause to add to the list. Lancet. 2016;387(10027):1486-88.

Cao-Lormeau V, Blake A, Mons S, Lastère S, Roche C, Vanhomwegen J et al. Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet. 2016;387(10027) 1531-39.

Schuler-Faccini L, Ribeiro EM, Feitosa IML, Cavalcaante DP, Pessoa A, Doriqui MJR, et al. Possible Association Between Zika Virus Infection and Microcephaly - Brazil, 2015. MMWR Morb Mortal Wkly Rep. 2016;65(3): 59-62.

Kohashi BSO, Ribeiro EOA, Soares KS, Prestes GBR. Abordagem preventiva e educativa em paciente odontológico com microcefalia associada ao Zika virus: relato de caso. Arch Health Invest. 2019;8(1):33-8

Queiroz VKP, Soares DM. Pesquisas odontológicas relacionadas com microcefalia: um estudo bibliométrico. Arch Health Invest. 2019;8(11):681-85.

Freitas PSS, Bussinger ECA, Lacerda LCX, Soares GB, Maciel ELN. O surto de Zika vírus: produção científica após Declaração de Emergência Nacional em Saúde Pública. Arch Health Invest. 2018;7(1):12-6.

Broutet N, Krauer F, Riesen M, Khalakdina A, Almiron M, Aldighieri S, Espinal M, Low N, Dye C. Zika Virus as a Cause of Neurologic Disorders. N Engl J Med. 2016;374(16):1506-9.

Leite CN, Varellis MLZ. Microcefalia e a odontologia brasileira. J Health NPEPS. 2016; 1(2):297-304.

Moura da Silva AA, Ganz JS, Sousa PD, Doriqui MJ, Ribeiro MR, Branco MD. Early Growth and neurologic outcomes of Infants with probable congenital Zika Virus Syndrome. Emerg Infect Dis. 2016;22(11):1953-56.

Tappe D, Nachtigall S, Kapaun Um, Schnitzler P, Günther S, Schmidt-Chanasit J. Acute Zika virus infection after travel to Malaysian Borneo, September 2014. Emerg Infect Dis. 2015;21(5):911-13.

Foy BD, Kobylinski KC, Foy JL, Blitvich BJ, Travassos da Rosa A, Haddow AD, et al. Provável Transmissão Não Vetorial de Zika Virus. Emerg Infect Dis. 2011;17(5):880-82.

Consolaro A, Francischone LA, Consolaro RB. Hipoplasia do esmalte: fundamentos para nomenclatura e identificação dos tipos e causas. Revista Dental Press de Estética. 2011;8(3):126-34.

Gardner J, Rudd PA, Prow NA, Belarbi E, Roques P, Larcher T et al. Infectious chikungunya virus in the saliva of mice, monkeys and humans. PLoS One. 2015;10(10):e0139481.

Powers AM, Logue CH. Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus. J Gen Virol. 2007;88(Pt 9):2363-77.

Thiberville SD, Moyen N, Dupuis-Maguiraga L, Nougairede A, Gould EA, Roques P, de Lamballerie X. Chikungunya fever: epidemiology, clinical syndrome, pathogenesis and therapy. Antiviral Res. 2013;99(3):345-70.

Chopra A, Anuradha V, Ghorpade R, Saluja M. Acute Chikungunya and persistent musculoskeletal pain following the 2006 Indian epidemic: a 2-year prospective rural community study. Epidemiol Infect. 2012;140(5):842-50.

Chopra A, Anuradha V, Lagoo-Joshi V, Kunjir V, Salvi S, Saluja M. Chikungunya virus aches and pains: an emerging challenge. Arthritis Rheum. 2008;58(9):2921-2.

Madariaga M, Ticona E, Resurrecion C. Chikungunya: bending over the Americas and the rest of the world. Braz J Infect Dis. 2016;20(1):91-8.

Manimunda SP, Vijayachari P, Uppoor R, Sugunan AP, Singh SS, Rai SK et al. Clinical progression of chikungunya fever during acute and chronic arthritic stages and the changes in joint morphology as revealed by imaging. Trans R Soc Trop Med Hyg. 2010;104(6):392-99.

Simon F, Javelle E, Cabie A, Bouquillard E, Troisgros O, Gentile G et al. French guidelines for the management of chikungunya (acute and persistent presentations). November 2014. Med Mal Infect. 2015;45(7):243-63.

Suryawanshi SD, Dube AH, Khadse RK, Jalgaonkar SV, Sathe PS, Zawar SD et al. Clinical profile of chikungunya fever in patients in a tertiary care centre in Maharashtra, India. Indian J Med Res. 2009;129(4):438-41.

Lahariya C, Pradhan SK. Emergence of the Chikungunya virus in the Indian subcontinent after 32 years: a review. J Vect Borne Dis. 2006;43:151-60.

Mourya D, Yadav P. Vector biology of dengue & chikungunya viruses. Indian J Med Res. 2006; 124(5):475-80.

Agarwal A, Joshi G, Nagar DP, Sharma AK, Sukumaran D, Pant SC et al. Mosquito saliva induced cutaneous events augment Chikungunya virus replication and disease progression. Infect Genet Evol. 2016;40:126-35.

Lum FM, Ng LF. Cellular and molecular mechanisms of chikungunya pathogenesis. Antiviral Res. 2015;120:165-74.

Katti R , Shahapur PR , Udapudi KL. Impact of chikungunya virus infection on oral health status: An observational study.Indian J Dent Res. 2011;22(4):613.

Pincus LB, Grossman ME, Fox LP. The exanthem of dengue fever: Clinical features of two US tourists traveling abroad. J Am Acad Dermatol. 2008;58(2):308-16.

Denis CK, Cavalcanti KM, Meirelles RC, Martinelli B. Manifestações otorrinolaringológicas em pacientes com dengue. Rev Bras Otorrinolaringol. 2003;69(5):644-47.

Itoda I, Masuda G, Suganuma A, Imamura A, Ajisawa A, Yamada K, Yabe S, Takasaki T, Kurane I, Totsuka K, Negishi M. Clinical features of 62 imported cases of dengue fever in Japan. Am J Trop Med Hyg. 2006 Sep;75(3):470-74.

Lolekha R, Chokephalbulkit K K, Yoksan S, Vanprapar N, Phongsmart W, Chearskul S.Diagnosis of dengue infection using various diagnostic tests in the early stage of illness. J Trop Med Public Health. 2004;35(2):391-95.

Siqueira WL, Moffa EB, Mussi MC, Machado MA. Zika virus infection spread through saliva-a truth or myth? Braz oral res. 2016;30(1):46

Hayes, Edward B. Zika Virus Outside Africa. Emerging Infectious. Diseases. 2015; 15(9):1347-50.

Musso D, Teissier A, Rouault E, Teururai S, de Pina JJ, Nhan TX. Detection of Zika virus in saliva and urine Virol J. 2016;13(1):120.

Bingham AM, Cone M, Mock V, Heberlein-Larson L, Stanek D, Blackmore C, et al.Comparison of test results for Zika Virus RNA in urine, serum, and saliva specimens from persons with travel-associated Zika Virus Disease - Florida, 2016. MMWR Morb Mortal Wkly Rep.2016;65(18):475-78.

Itoda I, Masuda G, Suganuma A, Imamura A, Ajisawa A, Yamada K et al. Clinical features of 62 imported cases of dengue fever in Japan. Am J Trop Med Hyg. 2006;75(3): 470-74.

Hamel R , Liégeois F , Wichit S , Pompon J , Diop F , Talignani L et al. Zika virus: epidemiology, clinical features and host-virus interactions. Microbes Infect. 2016;18 (7-8):441-49.

Oehler E, Watrin L, Larre P, Leparc-Goffart I, Lastere S, Valour F, Baudouin L, Mallet H, Musso D, Ghawche F. Zika virus infection complicated by Guillain-Barre syndrome--case report, French Polynesia, December 2013. Euro Surveill. 2014;19(9):20720.

Mysorekar IU, Diamond MS. Modeling Zika Virus Infection in Pregnancy. N Engl J Med. 2016;375(5):481-84.

Bandyopadhyay D, Ghosh SK. Mucocutaneous manifestations of Chikungunya fever. Indian J Dermatol. 2010;55(1):64-7.

Coffey LL, Failloux AB, Weaver SC. Chikungunya virus-vector interactions. Viruses. 2014;6(11):4628-63.

Couderc T, Lecuit M. Chikungunya Virus pathogenesis: From bedside to bench. Antiviral Res. 2015;121:120-31.

Rodríguez-Morales AJ, Cardona-Ospina JA, Fernanda Urbano-Garzón S, Sebastian Hurtado-Zapata J. Prevalence of Post-Chikungunya Infection Chronic Inflammatory Arthritis: A Systematic Review and Meta-Analysis. Arthritis Care Res (Hoboken). 2016;68(12):1849-58.

Publicado
2020-10-22
Como Citar
Oliveira, A. A. de, Lacerda, M. G. de A., Barros, A. A. de O., Barreto, J. O., Cruz, J. H. de A., Freire, J. C. P., & Ribeiro, E. D. (2020). Manifestações orais de arboviroses com ênfase em dengue, zika e chikungunya: revisão de literatura. ARCHIVES OF HEALTH INVESTIGATION, 10(2), 323-328. https://doi.org/10.21270/archi.v10i2.4677
Seção
Original Articles