Therapeutic alternative for oral lichen planus treatment in an unusual location: case report

  • Thaís Torres Barros Dutra Doutoranda, Departamento de Patologia Oral, Faculdade de Farmácia, Odontologia e Enfermagem (FFOE), Universidade Federal do Ceará (UFC), 60430-355 Fortaleza - CE, Brazil
  • Thâmara Manoela Marinho Bezerra Pós-Doutoranda, Departamento de Patologia Oral, Faculdade de Farmácia, Odontologia e Enfermagem (FFOE), Universidade Federal do Ceará (UFC), 60430-355 Fortaleza - CE, Brazil
  • Filipe Nobre Chaves Professor Adjunto, Mestrado em Ciências da Saúde, Curso de Odontologia, Universidade Federal do Ceará, Campus Sobral, 62010-820 Sobral - CE, Brazil
  • Sthefane Gomes Feitosa Doutoranda, Departamento de Patologia Oral, Faculdade de Farmácia, Odontologia e Enfermagem (FFOE), Universidade Federal do Ceará (UFC), 60430-355 Fortaleza - CE, Brazil
  • Fábio Wildson Gurgel Costa Professor Adjunto, Departamento de Radiologia Odontológica, Faculdade de Farmácia, Odontologia e Enfermagem (FFOE), Universidade Federal do Ceará (UFC), 60430-355 Fortaleza - CE, Brazil
  • Karuza Maria Alves Pereira Professora Associada, Departamento de Morfologia, Faculdade de Medicina (FAMED), Universidade Federal do Ceará (UFC), 60430-160 Fortaleza - CE, Brazil
Palavras-chave: Lichen Planus, Lichen Planus, Oral, Lip, Pharmaceutical Preparations

Resumo

Oral Lichen Planus (OLP) is considered a potentially malignant lesion (PML), although its rate of transformation is controversial. New treatments have been introduced recently, for example calcipotriene (D3 vitamin analog). Its incremental action with glucocorticoids is observed and isolated lip lesions may respond positively to combined topical therapy. Thus, objective of this case report is to show a therapeutic alternative for isolated and persistent OLP lip lesions. An 18-year-old teenager was referred to evaluate an erythematous lower lip lesion with approximately 10 years of evolution. The inspection revealed multiple erythematous areas surrounded by thin whitish streaks located in the vermilion of the lower lip. No abnormalities in the skin, nails, scalp or other areas of oral mucosa were observed. The incisional biopsy was performed and the microscopic exam showed areas of basal layer degeneration with intense mononuclear inflammatory infiltrate banded and predominantly subepithelial. The therapeutic proposal was topical application of Daivobet®, a combination of topical corticosteroids and vitamin D derivative. The lesion had remission after the fifteen days, medication was suspended and indicated when there was a relapse. During follow-up, no recurrences or complications were observed. That combination therapy may be a new approach in treating OLP.

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Publicado
2021-05-17
Como Citar
Dutra, T. T. B., Bezerra, T. M. M., Chaves, F. N., Feitosa, S. G., Costa, F. W. G., & Pereira, K. M. A. (2021). Therapeutic alternative for oral lichen planus treatment in an unusual location: case report. ARCHIVES OF HEALTH INVESTIGATION, 10(5), 734-739. https://doi.org/10.21270/archi.v10i5.4970
Seção
Original Articles