Uso da saliva como um espécime alternativo para diagnóstico de COVID-19: uma revisão sistemática

  • Samuel Gomes da Silva Teles
  • Maria Cecília Simões Riscado de Castro
  • Sabrina Nogueira Dutra
  • Lídia Márcia Silva Santos

Resumo

Introdução: O padrão ouro atual para detectar o RNA de SARS-CoV-2 é por reação em cadeia da polimerase em tempo real de transcrição reversa (RT-rtPCR) em swabs nasofaríngeos (NPS). Por esse motivo, a demanda pelos NPS aumentou e sua escassez se tornou uma realidade em muitos países. Com isso o uso da saliva se mostra uma alternativa promissora na triagem epidemiológica além de ser de fácil coleta e não invasiva. Objetivo: realizar uma revisão sistemática da literatura para avaliar o uso da saliva como um espécime alternativo para a detecção de SARS-CoV-2. Metodologia: A pesquisa sistemática foi realizada em sete bancos de dados (PubMed, Cochrane Library, Lilacs, Scielo, Web of Science, Scopus e Google Scholar) usando a variação dos termos de pesquisa (COVID-19 OR SARS-CoV-2 OR 2019-nCoV) AND "Saliva" no ano de 2020, recuperando 5480 publicações. Resultados: Após a leitura dos títulos e resumos, 411 textos foram conduzidos para leitura integral e 30 publicações foram consideradas para avaliação qualitativa do artigo. Conclusão: A saliva se apresenta um método alternativo eficaz para a detecção de SARS-CoV-2 e diagnóstico de COVID-19.

Descritores: Infecções por Coronavírus; Betacoronavirus; Saliva; Diagnóstico.

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Publicado
2020-10-06
Como Citar
Teles, S. G. da S., Castro, M. C. S. R. de, Dutra, S. N., & Santos, L. M. S. (2020). Uso da saliva como um espécime alternativo para diagnóstico de COVID-19: uma revisão sistemática. ARCHIVES OF HEALTH INVESTIGATION, 9(4). https://doi.org/10.21270/archi.v9i4.5114
Seção
Especial Covid-19