Multicenter investigation of predictors to self-report vaccination and seroprotection against Hepatitis B among healthcare workers

Autores

  • Vivianne Lins Ebrahim Morcerf Mestrado Profissional Pesquisa em Saúde, Centro Universitário Cesmac, 57051-530, Maceió-AL, Brasil
  • Celina Maria Costa Lacet Departamento de Gastroenterologia e Hepatologia, UNCISAL Universidade de Ciências da Saúde, 57010-300, Maceió-AL, Brasil
  • Álvaro Largura Laboratório Biovel, 85801-090, Cascavel-PR, Brasil
  • Evanio da Silva Laboratório Biovel, 85801-090, Cascavel-PR, Brasil
  • Kevan Guilherme Nóbrega Barbosa Mestrado Profissional Pesquisa em Saúde, Centro Universitário Cesmac, 57051-530, Maceió-AL, Brasil https://orcid.org/0000-0002-9410-7356
  • Sonia Maria Soares Ferreira Mestrado Profissional Pesquisa em Saúde, Centro Universitário Cesmac, 57051-530, Maceió-AL, Brasil
  • Silvio Romero de Oliveira Abreu Mestrado Profissional Pesquisa em Saúde, Centro Universitário Cesmac, 57051-530, Maceió-AL, Brasil

DOI:

https://doi.org/10.21270/archi.v10i8.5216

Palavras-chave:

Hepatitis B, Vaccination, Immunization, Health Personnel

Resumo

Objective: The Healthcare Workers (HCWs) are professionals with occupational exposure risk to Hepatitis B virus (HBV). Vaccination status has been widely explored; however, few investigations had confirmed the HBV immunity by serological test. Method: We performed a multicenter study based on a dual approach to understand the predictive factors of vaccination and seroprotection to HBV among HCWs. A cross-section design investigation was carried out among 371 workers from Alagoas state (Brazil); all of them from the public health service. Multiple Poisson Regression Models were constructed using vaccination and seroprotection as dependent factor. Results: The overall self-report of vaccination was 70.4% and the confirmation by immune response was 72.2%. Three predictive factors were associated with vaccination: education level; use of the PPE during work, and personal serological evaluation. Two predictive factors were associated with seroprotection: education level and use of the PPE during work. Conclusion: Our findings showed some evidence that almost one third of healthcare workers were not immune to HBV, and factors such as education and use of the protective equipment can predict the susceptibility to HBV.

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Referências

Mast EE, Margolis HS, Fiore AE, Brink EW, Goldstein ST, Wang SA. A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) part 1: immunization of infants, children, and adolescents. MMWM Recomm Rep. 2005;54(RR-16):1-31.

Morowatishaifabad M, Sakhvidi MJ, Gholianavval M, Boroujeni DM, Alavijeh MM. Predictors of hepatitis B preventive behavioral intentions in healthcare workers. Saf Health Work. 2015;6(2):139-42.

Assunção AA, Araújo TM, Ribeiro RB, Oliveira SV. Hepatitis B vaccination and occupation exposure in the healthcare sector in Belo Horizonte, Southeastern Brazil. Rev Saude Publica. 2012;46(4):665-73.

Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de DST, Aids e Hepatites Virais. O manual técnico para o diagnóstico das hepatites virais. Brasília: MS 2015. 68p.

Department of Health & Human Services. Centers for Disease Control and Prevention – CDC. Division of Viral. Interpretation of hepatitis B serological test results. [cited 2018 Dec 5]. Available from: https://www.cdc.gov/hepatitis/

hbv/hbvfaq.htm.

Abebaw TA, Aderaw Z, Gebremichael B. Hepatitis B virus vaccination status and associated factors among health care workers in Shashemene Zonal Town, Shashemene, Ethiopia: a cross sectional study. BMC Res Notes. 2017;6(10):260.

Akibu M, Nurgi S, Tadese M, Tsega WD. Attitude and vaccination status of healthcare workers against hepatitis B infection in a teaching hospital, Ethiopia. Scientifica. 2018;ID:6705305. 8p.

Batra V, Goswami A, Dadhich S, Kothari D, Bhargava N. Hepatitis B immunization in healthcare workers. Annals of Gastroenterology. 2015;28(2):276-80.

World Health Organization. Hepatitis B, Fact sheet No. 204, updated July 2018. Available from: http://www.who.int/mediacentre/ factsheets/fs204/en/.

Pereira LM, Martelli CM, Merchán-Hamann E, Montarroyos UR, Braga MC, Lima ML et al. Population-Based multicentric survey of Hepatitis b infection and risk factor differences among three regions in Brazil. Am J Trop Med Hyg. 2009;81(2):240-47.

Contera-Moreno L, Andrade SM, Cury Pontes ER, Stief AC, Pompilio MA, Motta-Castro AR. Hepatitis B virus infection in a population exposed to occupational hazards: firefighters of a metropolitan region in central Brazil. Rev Soc Bras Med Trop. 2012;45(4):463-67.

Petruzziello A. Epidemiology of hepatitis B virus (HBV) and hepatitis C virus (HCV) related hepatocellular carcinoma. Open Virol J. 2018;12(Suppl-1, M3):26-32.

Aaron D, Nagu TJ, Rwegasha J, Komba E. Hepatitis B vaccination coverage among healthcare workers at national hospital in Tanzania: how much, who and why? BMC Infect Dis. 2017;17:786.

Bonanni P, Bonaccorsi G. Vaccination against Hepatitis B in health care workers. Vaccine. 2001;19(17-19):2389-94.

Ziglam H, El-Hattab M, Shingheer N, Zorgani A, Elahmer O. Hepatitis B vaccination status among healthcare workers in a tertiary care hospital in Tripoli, Libya. J Infect Public Health. 2013;6(4):246-51.

Chang MH, Chen DS. Prevention of hepatitis B. Cold Spring Harb Perspect Med. 2015;5:a021-493.

Divisão de Imunização. Vacina contra hepatite B. Rev Saúde Pública. 2006;40(6):1137-40.

Brasil. Ministério da Saúde. Secretaria de Políticas de Saúde. Programa Nacional de Hepatites Virais. Brasília: Ministério da Saúde, 2002. 64p.

Marques CC, Carvalheiro JR. Assessment of laboratory diagnostic network in the implementation of the Program for Viral Hepatitis Prevention and Control in São Paulo State, Brazil, 1997-2012. Epidemiol. Serv. Saude. 2017;26(3):513-24.

Andrade Neto EP, Dutra CS, Lima V, Goes P. Prevalence of occupational accidents and vaccination profile against hepatitis B between students and dental professionals: a pilot study. Arq Odontol. 2013;49(1):32-8.

Oliveira LC, Pontes JP. Frequency of hepatitis B immunity and occupational exposures to body fluids among brazilian medical students at a public university. Rev Inst Med Trop. 2010;52(5):247-51.

Instituto Brasileiro de Geografia e Estatística – IBGE. IBGE Cidades Alagoas. Available from: https://cidades.ibge.gov.br/brasil/al/panorama.

Governo do Estado de Alagoas. Secretaria de Estado da Saúde – Sesau. Unidades e Serviços. Available from: http://www.saude.al. gov.br/acesso-a-informacao/130-2/.

Garcia LP, Facchini LA. Hepatitis B vaccination among primary healthcare workers. Cad Saúde Pública. 2008;24(5):1130-140.

Stroffolini T, Petrosillo N, Ippolito G, Lopalco A, Sagliocca L, Adamo B. Hepatitis B vaccination coverage among healthcare workers in Italy. Infect Control Hosp Epidemiol. 1998;19(10):789-91.

Costa FM, Lima Martins AM, Santos Neto PE, Veloso DN, Magalhães VS, Ferreira RC. Is vaccination against hepatitis B a reality among primary health care workers? Rev Latino-Am Enfermagem. 2013;21(1):316-24.

Burmett RJ, François G, Mphahlele MJ, Mureithi JG, Africa PN, Satekge MM, et al. Hepatitis B vaccination coverage in healthcare workers in Gauteng Province, South Africa. Vaccine. 2011;29(25):4293-97.

Rossato EM, Ferreira J. Perforating injuries and vaccination against hepatitis B among health workers in the Municipality of Santa Rosa, State of Rio Grande do Sul, Brazil, 2008.

Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Programa Nacional de Imunizações. Coberturas vacinais no Brasil período: 2010 - 2014. Brasília: Ministério da Saúde, 2015. 31p.

Souza FO, Freitas PS, Araújo TM, Gomes MR. Hepatitis B and Anti-HBS vaccination among health workers. Cad Saúde Colet. 2015;23(2):172-79.

Souza FO, Araújo TM. Occupational exposure and hepatitis B vaccination among health care workers. Rev Bras Med Trab. 2018;16(1):36-43.

Publicado

2021-07-18

Como Citar

Morcerf, V. L. E. ., Lacet, C. M. C., Largura, Álvaro, Silva, E. da, Barbosa, K. G. N., Ferreira, S. M. S., & Abreu, S. R. de O. (2021). Multicenter investigation of predictors to self-report vaccination and seroprotection against Hepatitis B among healthcare workers. ARCHIVES OF HEALTH INVESTIGATION, 10(8), 1249–1256. https://doi.org/10.21270/archi.v10i8.5216

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Seção

Original Articles