Chemical injury induced by the use of topical imiquimod: case report


  • Anne Diollina Araújo Morais Federal University of Ceará Campus Sobral, UFC - Campus Sobral, 62010-560 Sobral – CE, Brazil
  • Gabrielle Oliveira Sousa University of Fortaleza, UNIFOR, 60811-905 Fortaleza – CE, Brazil
  • Valdelya Nara Pereira Aguiar Postgraduate Program, Health Sciences, Federal University of Ceará Campus Sobral, UFC - Campus Sobral, 62042-280 Sobral – CE, Brazil
  • Filipe Nobre Chaves Postgraduate Program, Health Sciences, Federal University of Ceará Campus Sobral, UFC - Campus Sobral, 62042-280 Sobral – CE, Brazil
  • Marcelo Bonifácio da Silva Sampieri Federal University of Ceará Campus Sobral, UFC- Campus Sobral, 62010-560, Sobral – CE, Brazil
  • Denise Hélen Imaculada Pereira Oliveira Postgraduate Program, Health Sciences, Federal University of Ceará Campus Sobral, UFC- Campus Sobral, 62042-280, Sobral – CE, Brazil



Pharmaceutical Preparations, Mouth Mucosa, Drug-Related Side Effects and Adverse Reactions


Chemical injury consists in damage caused by a substance when it comes into contact with living tissue. Certain drugs can cause this type of lesion in the oral mucosa. Imiquimod (INN) is an example. Erythema, edema, vesicles, erosions, ulcerations and inflammatory reactions are among the adverse effects associated with the use of INN. Nevertheless, since its effects disappear when terminating treatment, INN is still considered an essential drug in the treatment of condyloma acuminata, actinic cheilitis, superficial basal cell carcinoma and molluscum contagiosum. The objective of this work is to report a clinical case of a 34-year-old male patient presenting a symptomatic lesion on the lower and upper lip mucosa; while including a literature review on potential adverse effects when prescribing topical INN 5% for the oral mucosa.


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Como Citar

Morais, A. D. A., Sousa, G. O., Aguiar, V. N. P., Chaves, F. N., Sampieri, M. B. da S., & Oliveira, D. H. I. P. (2021). Chemical injury induced by the use of topical imiquimod: case report . ARCHIVES OF HEALTH INVESTIGATION, 10(9), 1525–1529.



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