Relationship among Periodontal Disease, Apical Periodontitis and Offspring Health


  • Maria Sara de Lima Coutinho Mattera Multicenter Post-Graduate Program in Physiological Sciences, SBFis, Department of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, Brazil
  • Thaís Verônica Saori Tsosura Multicenter Post-Graduate Program in Physiological Sciences, SBFis, Department of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, Brazil
  • Renato Felipe Pereira Multicenter Post-Graduate Program in Physiological Sciences, SBFis, Department of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, Brazil
  • Fernando Yamamoto Chiba Department of Preventive and Restorative Dentistry, São Paulo State University (UNESP), School of Dentistry, Araçatuba - SP, Brazil
  • Fernando Marani Multicenter Post-Graduate Program in Physiological Sciences, SBFis, Department of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, Brazil
  • Bianca Elvira Belardi Multicenter Post-Graduate Program in Physiological Sciences, SBFis, Department of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, Brazil
  • Gestter Willian Lattari Tessarin University Center North Paulista (UNORP), São José do Rio Preto, SP, Brazil
  • Rodrigo Martins dos Santos Multicenter Post-Graduate Program in Physiological Sciences, SBFis, Department of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, Brazil
  • Doris Hissako Matsushita Multicenter Post-Graduate Program in Physiological Sciences, SBFis, Department of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, Brazil



Fetal Development, Low Birth Weight, Periapical Periodontitis, Periodontal Diseases


The relationship between maternal health and the fetal environment has been widely discussed in recent decades. Several studies have shown that insults that occur during the perinatal period modify fetal development, leading to harmful long-term results that culminate in pathologies in adulthood. Periodontal diseases (PD) comprise a wide range of inflammatory conditions that affect the supporting structures of the teeth (the gingiva, bone and periodontal ligament). Apical periodontitis (AP) is an inflammation at the apex of the thoot root usually caused by infection by bacteria from the root canal system. The present study aims to show the effects of maternal oral inflammations on the offspring health. The study provides information that both, maternal PD and AP, have negative effects in the short and long-term on the offspring health. Thus, adequate oral health can prevent adverse pregnancy outcomes and permanent changes in adult offspring. That is, oral hygiene during pregnancy should be encouraged.


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Como Citar

Mattera, M. S. de L. C., Tsosura, T. V. S. ., Pereira, R. F. ., Chiba, F. Y., Marani, F., Belardi, B. E. . ., Tessarin, G. W. L., Santos, R. M. dos, & Matsushita, D. H. (2021). Relationship among Periodontal Disease, Apical Periodontitis and Offspring Health. ARCHIVES OF HEALTH INVESTIGATION, 11(1), 134–140.



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