Regeneração Pulpar: um Desafio Clínico
DOI:
https://doi.org/10.21270/archi.v11i2.5411Palavras-chave:
Endodontia, Preparo de Canal Radicular, RegeneraçãoResumo
A regeneração pulpar implica a resolução da inflamação crônica e restauração do tecido dentoalveolar danificado. O sucesso dela requer efeitos do controle da infecção, biomateriais e células-tronco. Este trabalho apresenta uma visão clínica da regeneração pulpar, abordando protocolos, vantagens e limitações. Realizou-se uma busca eletrônica na Bireme e Pubmed utilizando os termos: pulp revascularization, regenerative endodontics, regeneração, endodontia em associação ao operador AND. Foram incluídos apenas relatos de caso, séries de caso e ensaios clínicos. Ao final, 18 artigos satisfizeram os critérios de elegibilidade. Nenhum artigo foi excluído. Viu-se que a maioria dos dentes submetidos são imaturos, irrigados com hipoclorito de sódio, utilizam como medicação intracanal a pasta tri-antibiótica, são feitos com indução de coágulo, fazem uso do MTA como barreira coronal juntamente com cimento de ionômero de vidro, tendo resultado positivo da terapia imposta. A regeneração endodôntica é uma terapia promissora, mas apresenta alto custo, incerteza do sucesso terapêutico, possibilidade de pigmentação coronária e calcificação.
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Referências
Schmalz G, Smith AJ. Pulp development, repair, and regeneration: challenges of the transition from traditional dentistry to biolocically based therapies. J Endod. 2014;40(Suppl4):S2-5.
Simon SRJ, Tomson PL, Berdal A. Regenerative Endodontics: Regeneration or Repair? JOE. 2014;40(4S):S70-5.
Albuquerque MTP, Nagata JY, Soares AJ, Zaia AA. Pulp revascularization: an alternative treatment to the apexification of immature teeth. Rev Gaú Odontol. 2014;62(4): 401-10.
Cao Y, Song M, Kim E, Shon W, Chugal N, Bogen, G, et al. Pulp-dentin regeneration: Current State and Future Propects. J Dent Res. 2015; 94(11):1544-51.
Paryani K, Kim SG. Regenerative endodontic treatment of permanent teeth after completion of root development: a report of 2 cases. J Endod. 2013;39(7):929-34.
Pompeo DA, Rossi LA, Galvão CM. Revisão integrativa: etapa inicial do processo de validação de diagnóstico de enfermagem. Acta Paul Enferm. 2009; 22(4):434-38.
Galler KM. Clinical procedures for revitalization: current knowledge and considerations. Int Endod J. 2016;49(10):926-36.
Diogenes A, Ruparel NB.Regenerative endodontic procedures: clinical outcomes. Dent Clin North Am. 2017;61(1):111-25.
Bukhari S, Kohli MR Setzer F, Karabucak B. Outcomeof revascularization procedure: a retrospective case series. J Endod. 2016;42(12): 1752-59.
Feigin K, Shope B. Regenerative Endodontics. J Vet Dent. 2017;34(3):161-78.
Kahler B, Mistry S, Moule A, Ringsmuth AK, Case P, Thomson A et al. Revascularization outcomes: a prospective analysis of 16 consecutive cases. J Endod. 2014;40(3):333-38.
Nagata JY, Gomes BP, Rocha Lima TF, Murakami LS, de Faria DE, Campos GR et al. Traumatized immature teeth treated with 2 protocols of pulp revascularization. J Endod. 2014;40(5):606-12.
Li L, Pan Y, Mey L, Li J. Clinical and radiographic outcomes in immature permanent necrotic evaginated teeth treated with endodontic procedures. J Endod. 2017;43(2):246-51.
Song M, Cao Y, Shin S, Shon W, Chugal N, Kim RH et al. Revascularization associated intracanal calcification: assessment of prevalence and contributing factors. J Endod. 2017;43(12):2025-33.
Alagl A, Bedi S, Hassan K, AlHumaid J. Use of platelet-rich vital immature permanent teeth: clinical and cone-beam computed tomography evaluation. J Int Med res. 2017;45(2):583-93.
Asgary S, Fazlyab M, Nosrat A. Regenerative endodontic treatment versus apical plug in immature teeth: three-year follow-up. J Clin Pediatr Dent. 2016;40(5):356-60.
Žižka R, Buchta T, Voborná I, Harvan L, Šedý J. Root maturation in teeth treated by unsuccessful revitalization: 2 cases reports. J Endod. 2016;42(5):724-29.
Nagaveni NB Pathak S Poornima P Joshi JS. Revascularization induced maturogenesis of non-vital immature permanent tooth using platelet-rich-fibrin: a case report. J Clin Pediatr Dent. 2016;40(1):26-30.
Carmen L, Assunción M, Beatriz S, Rosa YV. Revascularization in immature permanent teeth with necrotic pulp and apical pathology: case series. Case rep Dent. 2017;2017:1-8.
Timmerman A, Parashos P. Bleaching of a discolored tooth with retrieval of remnants after successful regenerative endodontics. J Endod. 2018;44(1):93-7.
Nosrat A, Seifi A, Asgary S. regenerative endodontic treatment (revascularization) for necrotic immature permanente molars: a review and reporto f two cases with a new biomaterial. J Endod. 2011;37(4):562-67.
Ribeiro ECC, Santos M, Siqueira EL, Nicoletti MA. O hipoclorito de sódio na Endodontia. Braz J Health. 2010;1(1):54-62.
Lopes HP, Siqueira Junior JF. Endodontia: biologia e técnica. 3.ed. Rio de Janeiro: Guanabara Koogan; 2015.
Graham L, Cooper PR, Cassidy N, Nor JE, Sloan AJ, Smith AJ. The effect of calcium hydroxide on solubilisation of bio-active dentine matrix components. Biomaterials. 2006;27(14):2865-73.
Hargreaves KM, Giesler T, Henry M, Wang Y. Regeneration potential of the young permanent tooth: what does the future hold? J Endod. 2008;34(7):S51-6.
Araújo PRS, Silva LB, Neto APDS, Almeida de Arruda JA, Álvares PR, Sobral APV et al. Pulp revascularization: a literaure review. Open Dent J. 2017;10:48-56.
Ducret M, Fabre H, Celle A, Mallein-Gerin F, Perrier-Groult E, Alliot-Licht B et al. Current challenges in human tooth revitalization. Biomed Mater Eng. 2017;28(S1):S159-68.
Lin LM, Ricucci D, Huang GT. Regeneration of the dentine-pulp complex with revitalization therapy: challenges and hopes. Int Endod J. 2014;47(8):713-24.
He L, Kim SG, Gong Q, Zhong J, Wang S, Zhou X, et al. Regenerative endodontics for adults patient. J Endod. 2017;43(9S):S57-64.
Eramo S, Natali A, Pinna R, Milia E. Dental pulp regeneration via cell homing. Int Endod J. 2018;51(4):405-19.
Kim JY, Xin X, Moioli EK, Chung J, Lee CH, Chen M et al. Regeneration of dental-pulp-like tissue by chemotaxis-induced cell homing. Tissue Eng Part A. 2010;16(10):3023-31.
Kandemir Demirci G, Güneri P, Çalışkan MK. Regenerative endodontic therapy with platelet rich fibrin: case series. J Clin Pediatr Dent. 2020;44(1):15-9.