Reduced Levels of Salivary Melatonin in Individuals with Periodontal Disease: Systematized Review
DOI:
https://doi.org/10.21270/archi.v11i2.5280Keywords:
Periodontal Diseases, Melatonin, MouthAbstract
Objective: This literature review aims to identify and summarize studies that have assessed salivary melatonin levels in individuals with periodontal disease (PD). Methods: A systematic search for scientific publications was carried out in the following databases: PubMed, SCOPUS, LILACS, EMBASE, BIREME and SciELO, using the terms "Periodontal disease", "Melatonin" and "Saliva" in Portuguese and English. Results: There was a predominance of case-control studies; the articles showed levels of evidence and degrees of moderate recommendation that showed a decrease in the levels of salivary melatonin in subjects with PD compared to controls. Conclusion: Scientific evidence indicates that salivary melatonin levels are decreased in periodontal disease.
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