Chronic Sclerosing Sialadenitis: case report
DOI:
https://doi.org/10.21270/archi.v10i8.5444Keywords:
Sialadenitis, Salivary Glands, Mouth NeoplasmsAbstract
Chronic sclerosing sialadenitis was first described in Germany by Kuttner in 1896 is a benign tumorlike lesion predominately affecting the submandibular gland and is a relatively uncommon chronic inflammatory disease of the salivary gland. This lesion is characterized histologically by periductal fibrosis acinar atrophy, and gland infiltration by lymphocytes with lymphoid follicle formation, loss of the acini, and, eventually, marked sclerosis of the salivary gland and usually occurs in the elderly and middleaged adults with a slight male predominance. The report describes a patient R.J.R.C of a 53-year- old man, presenting with a two-years history of a painless, moderate sublingual mass related to a partial edentulism of the teeth 46 and 47.
Downloads
References
Küttner H. Über entzündliche tumoren der submaxillar-speicheldrü-se. Bruns’Beitr Klin Chir. 1896; 15: 815-828.
Seifert G. Tumour-like lesions of the salivary glands. The new WHO classification. Pathol Res Pract. 1992;188:836-46.
Seifert G, Sobin LH. The World Health Organization’s Histological Classification of Salivary Gland Tumors. A commentary on the second edition. Cancer. 1992;70:379-85.
Seifert G, Donath K. On the pathogenesis of the Küttner tumor of the submandibular gland -- Analysis of 349 cases with chronic sialadenitis of the submandibular. HNO. 1977;25:81-92.
Teymoortash A, Tiemann M, Schrader C, Werner JA. Characterization of lymphoid infiltrates in chronic obstructive sialadenitis associated with sialolithiasis. J Oral Pathol Med. 2004;33:300-4.
Martinez CN, Baquera HJ, Sánchez CR, Márquez RM, Ortiz Hidalgo C. Küttner’s tumour (chronic sclerosing sialadenitis) clinical, pathological and immunohistochemical study in 8 cases of a little-known entity. Acta Otorrinolaringol Esp 2007; 58(1):25-30.
Rasanen O, Jokinen K, Dammert K. Sclerosing inflammation of the submandibular salivary gland (Kuttner tumour). A progressive plasmacellular ductitis. Acta Otolaryngol 1972;74:297–301
Tiemann M, Teymoortash A, Schrader C, Werner JA, Parwaresch R, Seifert G, et al. Chronic sclerosing sialadenitis of the submandibular gland is mainly due to a T lymphocyte immune reaction. Mod Pathol. 2002;15:845-52.
Ikeda M, Ikui A, Tanaka M, Omori H, Tomita H. Immuno-histopathological investigation on unspecific chronic sclerosing sialadenitis of the submandibular gland (Kuttner tumor). Auris Nasus Larynx 1994;21:103–10.
Blanco M, Mesko T, Cura M, Cabello-Inchausti B. Chronic sclerosing sialadenitis (Kuttner’s tumor): unusual presentation with bilateral involvement of major and minor salivary glands. Ann Diagn Pathol. 2003;7:25-30.
Toussirot, É., & Roudier, J. Epstein–Barr virus in autoimmune diseases. Bestb practice & research Clinical rheumatology 2008, 22(5): 883-96.
Geyer JT, Ferry JA, Harris NL, Stone JH, Zukerberg LR, Lauwers GY, et al. Chronic sclerosing sialadenitis (Küttner tumor) is an IgG4-associated disease. Am J Surg Pathol. 2010;34:202-10.
